DEVELOPMENT OF FIRST ORDER DERIVATIVE ULTRAVIOLET SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF LEVOCETIRIZINE HYDROCHLORIDE AND PHENYLEPHRINE HYDROCHLORIDE IN BULK AND COMBINED DOSAGE FORM
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RP-HPLC method development for the estimation of Levocetirizine and Phenylephrine hydrochloride in combined dosage form
A rapid, accurate RP Levocetirizine and phenylephrine separation was achieved on column Luna 5u C18 (20mm X 4mm) using mobile phase of methanol: Pot. Dihydrogen Phosphate Buffer (pH 6.0), (70:30) .The UV detection was performed at 251nm with flow rate of 1.0 mL Phenylephrine hydrochloride was found to be 8.42 min and 2.70 min with mean recovery 100.64 & 100.40% respectively. The proposed method...
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ژورنال
عنوان ژورنال: International Research Journal of Pharmacy
سال: 2013
ISSN: 2230-8407
DOI: 10.7897/2230-8407.04523